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All the business information you need to know about is right here. Presented and researched by http://www.md-news.net. We've searched the information super highway far and wide to provide you with the best business site on the internet today. The links below will assist you in your efforts to find the information that you are looking for about
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You've probably heard of search engines such as Yahoo!, Google, and AltaVista. There are literally dozens of these tools to help you locate the business information you're looking for. The trick is understanding how they work, so you can use the right tool for the job and if the returned list of business sites is useable. We've done this and our summary below will save you hours and hours of time.


Search engines break down into two categories, directories and indexes. Directories, such as Yahoo!, are good at identifying general information but no so good and specific business information. Like a card catalog in a library, they classify websites into similar categories, such as accounting firms, English universities and business providers. The results of your search will be a list of websites related to your search term. For instance, if you are looking for the business, use a directory.

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Thousands of business e-stores now thrive on the Web, providing people with a way to purchase goods and services electronically. For small businesses, the Internet can deliver a global market. Depending on which survey you believe, that may be more than 350 million people, with another 500 million Internauts projected over the next few years. If the demographics of the online community match your business customer profile, that's a lot of potential new business. While the potential is there, however, challenges loom large.

Remember, it takes time for people to adopt to new technology and modes of transactions. Many people remain reluctant to give out their credit card numbers over the Internet for business purchases. But most analysts project healthy growth for business online sales, especially as security issues are addressed.

What is the Treatment for Bipolar Disorder?

 by: Michael G. Rayel, MD

How do we treat bipolar disorder? Specifically, how do we treat mania or depression associated with bipolar disorder? The treatment of these two clinical states is not the same.

The treatment of mania is dependent upon its severity and acuity. For mild to moderate mania, mood stabilizers such as lithium and valproic acid (Valproate) are still the standard of treatment and may be sufficient to contain the symptoms. Lithium starts to work after 10 to 14 days while valproic acid, about 7 to 10 days.

Also, recent studies have shown the effectiveness of atypical antipsychotics such as risperidone, olanzapine, and quetiapine even when used alone to treat the acute phase of bipolar disorder.

These drugs are relatively safe but they don't come without side effects. Nausea, vomiting, tremors, and dizziness during the initial phase of treatment are commonly experienced. The more serious side effects such as renal and thyroid problem from lithium, liver dysfunction and pancreatitis from valproic acid, and increased risk of diabetes and high cholesterol from atypical antipsychotics are uncommon. However, regular blood tests are required to monitor any abnormalities.

For moderate to severe cases, atypical antipsychotics such as risperidone and quetiapine should be added to the mood stabilizers during the acute phase. Once the illness has stabilized and the symptoms have subsided, then the atypical neuroleptics can be gradually tapered off. But the mood stabilizers should continue. Regardless of severity, patients usually do well on a combination of mood stabilizer and atypical antipsychotic during the acute phase.

What is the treatment for bipolar depression? In general, the mood stabilizers' dosage should be optimized or if the patient is not on any medication yet, a mood stabilizer such as lithium should be started. Physicians should make sure that the medication maintains a "therapeutic level." If not, the dosage should be adjusted. Moreover, possible precipitants such as stresses at home should be addressed.

If these measures don't help and the depression is so severe, an antidepressant with the least risk to induce mania such as bupropion should be added to the mood stabilizer. When the depression is resolved, then the antidepressant can be gradually tapered off because its prolonged use even in the presence of mood stabilizer can still induce mania.

When should the medication be discontinued? Bipolar patients have to continue taking the medication for several months even after they become normal. High relapse rate is common if medications are prematurely stopped. Also, for patients with multiple or difficult-to-treat episodes, they may need to take the medication for years or even for life to prevent recurrence.

Patients and their physicians should thoroughly discuss the risk and benefits of any treatment intervention. Knowledge about the drug's indication, side effects, and prognosis with or without treatment is a must.

Furthermore, it is crucial that bipolar patients should also receive individual psychotherapy to help them deal with the many personal and psychosocial issues they face on a daily basis. As you know, medication alone won't suffice to address financial problems, marital conflict, work issues, and prior abuse.

In summary, the combination of medication and psychotherapy is the best treatment for bipolar disorder.

About The Author

Copyright © 2004. Dr. Michael G. Rayel – author (First Aid to Mental Illness–Finalist, Reader's Preference Choice Award 2002) psychiatrist, and inventor of Oikos Game: A Personal Development and Emotional Skills Game. For more information, please visit http://www.oikosgame.com.

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